Independent Survey on Lithium Orotate Use

Help advance understanding of real-world lithium orotate supplementation

[Take Baseline Survey]

Purpose of This Study: We are conducting an independent, IRB-approved observational survey to better understand how adults in the United States use lithium orotate supplements in everyday practice.

The goal is to describe:

• Typical dose ranges

• Reasons for use

• Patterns of long-term use

• Self-reported experiences (positive, neutral, or negative)

This study does not evaluate specific brands and does not make claims about effectiveness.

Why This Study Is Being Done: Recent basic-science and translational research, including a 2025 Nature paper reporting associations between lithium deficiency and Alzheimer’s disease risk, has increased scientific interest in low-dose lithium exposure. At the same time, real-world human usage patterns for lithium orotate supplements remain largely undocumented.

This survey aims to help close that gap by collecting de-identified, descriptive data on how lithium orotate is currently used outside of clinical trials.

Who Can Participate: You may be eligible if you:

• Are 18 years of age or older

• Currently take lithium orotate, previously took lithium orotate, or are considering taking it

Participation is voluntary.

What Participation Involves

• One online survey (approximately 10–15 minutes)

• No product purchase required

• No medical advice provided

• No identifying personal information collected

You may skip any question and may stop at any time.

Independence & Transparency: This study is:

• Investigator-initiated

• IRB-approved

• Non-commercial

• Independent of supplement manufacturers

Survey responses are analyzed only in aggregate. Individual-level data are never shared.


Begin the Survey: [Take Baseline Survey]

Estimated time: 10–15 minutes

Frequently Asked Questions

Does this study recommend lithium orotate?

No. This study does not provide medical recommendations.

Will I receive results?

Aggregated summaries may be posted on the study website as they become available.

Can I stop at any time?

Yes. Participation is entirely voluntary.

Disclaimer:

  • This registry does not provide medical advice. Do not start, stop, or change supplements or medications based on this survey.

  • Some visitors may arrive at this page via links shared by supplement manufacturers as an educational resource. Manufacturers do not sponsor this study and have no access to survey data.

Contact

For questions about this study, please contact:

  • owensp@winthrop.edu (study team)

Verification / Official Study Page:

This registry is an IRB-approved Winthrop University human-subjects research study and is not affiliated with any supplement company.

Official communications will come only from:

  • owensp@winthrop.edu (study team)

  • smithmr@winthrop.edu (Winthrop University IRB)

⚠️ Fraud warning: If a page asks you to purchase supplements, provides different contact emails, or requests payment, it is not this study.